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- 作者: 刘成星,李敏,解军 ( 太原师范学院生物系;山西医科大学基础医学院 )
- 出处: 2524 2018 第41卷 第3期 P208-212
- 关键词: 神经管畸形 胚胎神经上皮细胞 微管吸吮 黏弹性 细胞变形能力
- 摘要: 目的 探索胚胎神经上皮细胞力学特性与神经管闭合之间的关系.方法 用全反式维甲酸对胚胎发育第7.5天的小鼠进行灌胃处理,制备小鼠神经管畸形(NTDs)模型.分别于胚胎发育第9.5天与11.5天处死孕鼠,提取正常及神经管畸形原代神经上皮细胞,采用微管吸吮技术结合标准固体黏弹性力学模型分析神经上皮细胞的力
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点击量:3
- 作者: 刘成星,李敏,解军 ( 太原师范学院生物系;山西医科大学基础医学院 )
- 出处: 3174 2018 第41卷 第3期 P208-212
- 关键词: 神经管畸形 胚胎神经上皮细胞 微管吸吮 黏弹性 细胞变形能力
- 作者: 杜根来,李晓娜,陈维毅,刘成星,王晓君,贺瑞 ( 太原理工大学应用力学与生物医学工程研究所;太原师范学院生物系;山西省眼科医院准分子激光室 )
- 出处: 917 2017 第6期 P1007-1013
- 关键词: 圆锥角膜 炎性因子 周期性牵拉 基质金属蛋白酶 基质金属蛋白酶抑制剂
- 摘要: 研究肿瘤坏死因子-α与机械牵拉对圆锥角膜成纤维细胞白细胞介素-6、基质金属蛋白酶-1,-3、组织基质金属蛋白酶抑制剂-1,-2基因表达与蛋白合成的影响。对体外培养的圆锥角膜成纤维细胞进行牵拉幅度12%、频率0.1Hz的周期性牵拉6h,并给予1ng/mL TNF-α处理,采用Real-Time PCR
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点击量:1
- 发明人: 李晓娜,刘成星,王晓君 ( 太原理工大学,太原师范学院 )
- 申请人: 太原理工大学,太原师范学院
- 申请号: 201610412839.5
- 申请日期: 2016.06.13
- 摘要: 本发明涉及一种测量装置及其具体的测量操作方法,具体是一种连续测量薄膜变形的装置及方法。一种连续测量薄膜变形的装置,包括万能材料试验机,所述万能材料试验机包括外接端、检测分析装置和显示屏,检测分析装置和显示屏电连接并由显示屏显示分析后的图像,还包括位移传感器,所述位移传感器固定在万能材料试验机的外接端
期刊
- 作者: Pengfei Feng,Xiaona Li,Weiyi Chen,Chengxing Liu,Shuo Rong,Xiaojun Wang,Genlai Du,Feng, Pengfei ,Li, Xiaona ,Chen, Weiyi ,Liu, Chengxing ,Rong, Shuo ,Wang, Xiaojun ,Du, Genlai ( 1 Institute of Applied Mechanics and Biomedical Engineering, Taiyuan University of Technology, Taiyuan 030024, China 2 Biology Department, Taiyuan Normal University, Jinzhong 030619, China 3 College of Mechanics, Taiyuan University of Technology, Taiyuan 030024, China 4 Institute of Applied Mechanics and Biomedical Engineering, Taiyuan University of Technology, Taiyuan, 030024, China 5 Biology Department, Taiyuan Normal University, Jinzhong, 030619, China 6 College of Mechanics, Taiyuan University of Technology, Taiyuan, 030024, China )
- 出处: 550 2016 Vol.15 P1-10
- 关键词: Corneal fibroblasts Cyclic stretching Interleukin-1β Matrix metalloproteinases
- 摘要: Background: Corneal tensile strain increases if the cornea becomes thin or if intraocular pressure increases. However, the effects of mechanical stres
期刊
- 作者: Genlai Du,Chengxing Liu,Xiaona Li,Weiyi Chen,Rui He,Xiaojun Wang,Pengfei Feng,Weiwei Lan ( 1 Shanxi Key Lab of Material Strength & Structural Impact, Taiyuan University of Technology, Taiyuan 030024, China 2 Department of Biology, Taiyuan Normal University, Taiyuan 030031, China 3 Department of Excimer Laser, Shanxi Eye Hospital, Taiyuan 030002, China )
- 出处: 556 2016 Vol.241 No.18 P2033-2041
- 关键词: Corneal fibroblasts inflammatory cytokine keratoconus matrix metalloproteinases
- 摘要: Inflammatory molecules and matrix metalloproteinase (MMPs) have been found over-expressed in the tear film of patients with keratoconus. However, the
期刊
- 作者: Pengfei Feng,Xiaona Li,Weiyi Chen,Chengxing Liu,Shuo Rong,Xiaojun Wang,Genlai Du ( 1.Institute of Applied Mechanics and Biomedical Engineering,Taiyuan University of Technology,Taiyuan,China;2.College of Mechanics,Taiyuan University of Technology,Taiyuan,China;3.Biology Department,Taiyuan Normal University,Jinzhong,China )
- 出处: 550 2016 Vol.15 P63
- 关键词: Cyclic stretching Interleukin-1β Corneal fibroblasts Matrix metalloproteinases
- 摘要: Background Corneal tensile strain increases if the cornea becomes thin or if intraocular pressure increases. However, the effects of mechanical stress
期刊
- 作者: Pengfei Feng,Xiaona Li,Weiyi Chen,Chengxing Liu,Shuo Rong,Xiaojun Wang,Genlai Du,Feng, Pengfei ,Li, Xiaona ,Chen, Weiyi ,Liu, Chengxing ,Rong, Shuo ,Wang, Xiaojun ,Du, Genlai ( 1 Institute of Applied Mechanics and Biomedical Engineering, Taiyuan University of Technology, Taiyuan 030024, China 2 Biology Department, Taiyuan Normal University, Jinzhong 030619, China 3 College of Mechanics, Taiyuan University of Technology, Taiyuan 030024, China 4 Institute of Applied Mechanics and Biomedical Engineering, Taiyuan University of Technology, Taiyuan, 030024, China 5 Biology Department, Taiyuan Normal University, Jinzhong, 030619, China 6 College of Mechanics, Taiyuan University of Technology, Taiyuan, 030024, China )
- 出处: 550 2016 Vol.15 P1-10
- 关键词: Corneal fibroblasts Cyclic stretching Interleukin-1β Matrix metalloproteinases
- 摘要: Background: Corneal tensile strain increases if the cornea becomes thin or if intraocular pressure increases. However, the effects of mechanical stres