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Sodium fluoride induces apoptosis in the kidney of rats through caspase-mediated pathways and DNA damage.

  • 【作者】Guo Hua Song ,Ji Ping Gao ,Chun Fang Wang ,Chao Yang Chen ,Xiao Yan Yan ,Min Guo ,Yu Wang ,Fu Bing Huang
  • 【刊名】Journal of Physiology and Biochemistry
  • 【作者单位】1. Laboratory Animal Center, Shanxi Medical University, Road Xinjian 56, Taiyuan, 030001, China 2. Department of Biology, Taiyuan Normal University, Taiyuan, 030031, China
  • 【年份】2014
  • 【卷号】Vol.70 No.3
  • 【页码】857-868
  • 【ISSN】1138-7548
  • 【关键词】Sodium fluoride Kidney Apoptosis Caspase DNA damage 
  • 【摘要】 Long-term excessive sodium fluoride (NaF) intake can cause many bone diseases and nonskeletal fluorosis. The kidneys are the primary organs involved in the excretion and retention of NaF. The objective of the present study was to determine the effect...
  • 【文献类型】 期刊
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