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Fluoride induces apoptosis and alters collagen I expression in rat osteoblasts

  • 【作者】Xiaoyan Yan,Xiaoting Yan,Alex Morrison,Tianlong Han,Qinglin Chen,Ji Li and Jundong Wang
  • 【刊名】Toxicology Letters
  • 【作者单位】a Shanxi Key Laboratory of Ecological Animal Science and Environmental Medicine, Shanxi Agricultural University, Taigu, Shanxi 030801, PR China b Department of Biology, Taiyuan Normal University, Taiyuan, Shanxi 030012, PR China c Department of Pharmacology and Toxicology, School of Medicine and Biomedical Sciences, University at Buffalo-SUNY, Buffalo, NY 14214, USA d Graduate School of Shanxi Medical University, Taiyuan, Shanxi 030001, PR China
  • 【年份】2011
  • 【卷号】Vol.200 No.3
  • 【页码】133-138
  • 【ISSN】0378-4274
  • 【关键词】Fluoride Osteoblasts Cell cycle Apoptosis Collagen I 
  • 【摘要】 In this study we investigated apoptosis and expression of the collagen I gene in newborn rat osteoblasts (OB) by the administration of varying concentrations of fluoride (F). Sodium fluoride (NaF) at concentrations of 0, 0.5, 5, 10, and 20 mg/L was a...
  • 【文献类型】 期刊
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