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Positive effects of the young systemic environment and high GDF-11 levels on chondrocyte proliferation and cartilage matrix synthesis in old mice.

  • 【作者】Lu,Li ,Xiaochun,Wei ,Dongming,Wang ,Zhi,Lv ,Xiang,Geng ,Pengcui,Li ,Jiangong,Lu ,Kaihang,Wang ,Xiaohu,Wang ,Jian,Sun ,Xiaoming,Cao ,Lei,Wei
  • 【刊名】Arthritis & rheumatology (Hoboken, N.J.)
  • 【作者单位】Department of Orthopedics '(1)' ; Shanxi Key Laboratory of Bone and Soft Tissue Injury Repair [2] ; The Second Hospital of Shanxi Medical University [3] ; No. 382 [4] ; Wuyi Road [5] ; Taiyuan [6] ; 030001 [7] ; China. [8] ; Department of Pharmacy [9] ; Shanxi Health Vocational College [10] ; No. 100 [11] ; Wenjin Road [12] ; Jinzhong [13] ; 030619 [14] ; The Subsidiary High School of Taiyuan Normal University [15] ; Warren Alpert Medical School of Brown University [16] ; Suite 402A [17] ; 1 Hoppin Street [18] ; Providence [19] ; RI [20] ; 02903 [21] ; USA. [22]
  • 【摘要】 To investigate the effects of a young systemic environment and GDF11 on aging cartilage. A heterochronic parabiosis model , isochronic parabiosis model , and 12-month-old mice alone were evaluated. Knee joints and chondrocytes of old mice were exami...
  • 【文献类型】 期刊
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