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Positive effects of the young systemic environment and high GDF-11 levels on chondrocyte proliferation and cartilage matrix synthesis in old mice.

  • 【作者】Lu Li,Xiaochun Wei,Dongming Wang,Zhi Lv,Xiang Geng,Pengcui Li,Jiangong Lu,Kaihang Wang,Xiaohu Wang,Jian Sun,Xiaoming Cao,Lei Wei
  • 【刊名】Arthritis & rheumatology (Hoboken, N.J.)
  • 【作者单位】Department of Orthopedics, Shanxi Key Laboratory of Bone and Soft Tissue Injury Repair, The Second Hospital of Shanxi Medical University, No. 382, Wuyi Road, Taiyuan, 030001, China. Department of Pharmacy, Shanxi Health Vocational College, No. 100, Wenjin Road, Jinzhong, 030619, China. The Subsidiary High School of Taiyuan Normal University, Taiyuan, 030001, China. Department of Orthopedics, Warren Alpert Medical School of Brown University, Suite 402A, 1 Hoppin Street, Providence, RI, 02903, USA.
  • 【年份】2020
  • 【ISSN】2326-5205
  • 【摘要】 OBJECTIVE: To investigate the effects of a young systemic environment and GDF11 on aging cartilage. METHODS: A heterochronic parabiosis model , isochronic parabiosis model , and 12-month-old mice alone were evaluated. Knee joints and chondrocytes of...
  • 【文献类型】 期刊
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