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Synthesis, biological activity and toxicity of chromium metformin complex as potential insulin-mimetic agent in C57BL/6 mice

  • 【作者】Dong, Jinlong,Liu, Bin,Liang, Gang,Yang, Binsheng
  • 【刊名】Journal of Coordination Chemistry
  • 【作者单位】a Key Laboratory of Chemical Biology of Molecular Engineering of Education Ministry, Institute of Molecular Science, Shanxi University, Taiyuan, China; b Department of Chemistry, Taiyuan Normal University, Taiyuan, China; c Department of Pathology, First Hospital of Shanxi Medical University, Taiyuan, China
  • 【年份】2018
  • 【卷号】Vol.71 No.10
  • 【页码】1526-1541
  • 【ISSN】0095-8972
  • 【关键词】biological activity Chromium complex cytotoxicity metformin oral toxicity 
  • 【摘要】 As an oral hypoglycemic agent, metformin has become a best-selling inexpensive drug worldwide. In this thesis, [Cr 3 ] complex was synthesized and characterized by elemental analysis , electrospray ionization mass spectrometry , nuclear magnetic re...
  • 【文献类型】 期刊
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