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Aminocaproylated nanodiamond prodrug for tumor intracellular enhanced delivery of doxorubicin

  • 【作者】Chen, Le,Li, Lin
  • 【刊名】Journal of Drug Delivery Science and Technology
  • 【作者单位】a School of Pharmaceutical Science, Shanxi Medical University, Taiyuan, 030001, China; b Department of Chemistry, Taiyuan Normal University, Jinzhong, 030619, China
  • 【年份】2020
  • 【卷号】Vol.60
  • 【ISSN】1773-2247
  • 【关键词】Acylhydrazone linkage Aminocaproic acid DOX Nanodiamond pH-activatable 
  • 【摘要】 It is urgent to improve the stability of drug system and enhance the curative effect of efficient cancer chemotherapy. In this study, an aminocaproic acid modified nanodiamond-based prodrug with pH-activatable fluorescence and cytotoxicity was desig...
  • 【文献类型】 期刊
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