【作者单位】Affiliations 1 College of Biological Sciences and Technology, Taiyuan Normal University, Jinzhong, China. 2 Institute of Basic and Translational Medicine, Xi'an Medical University, Xi'an, China.
【摘要】 Metallo-β-lactamases hydrolyze and inactivate β-lactam antibiotics, are a pivotal mechanism conferring resistance against bacterial infections. SMB-1, a novel B3 subclass of MβLs from Serratia marcescens could deactivate almost all β-lactam antibiot...