Evaluation of intracellularly targeted engineered antioxidant fusion proteins SOD-LCA2 and Prx-LCA2 as promising therapeutic combinations for alleviating and restoring pulmonary oxidative damage
【作者】Di Liu，Jiaqi Qu，Yafen Zhan，Xiaoying Wu，Hongping Qiao，Yeli Zhang，Na Li，Bo Li
【刊名】International Journal of Biological Macromolecules
【作者单位】1College of Biological Sciences and Technology and Center for Veterinary Medicine, Taiyuan Normal University, Jinzhong 030619, Shanxi, China;2School of Environmental Science and Engineering, Taiyuan University of Technology, Taiyuan, 030024, Shanxi, China
【年份】2025
【页码】145627
【ISSN】0141-8130
【摘要】 The lungs, as the sole internal organs directly interfacing with the external environment, are particularly susceptible to oxidative stress. To address the challenge of intracellular antioxidant delivery, a bifunctional fusion protein system was deve...
