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Protective immunity induced by peptides of AMA1, RON2 and RON4 containing T-and B-cell epitopes via an intranasal route against toxoplasmosis in mice

  • 【作者】Zhang, T.-E.,Yin, L.-T.,Li, R.-H.,Wang, H.-L.,Meng, X.-L.,Yin, G.-R.
  • 【刊名】Parasites and Vectors
  • 【作者单位】a Research Institute of Medical Parasitology, Shanxi Medical University Xinjian, South Road, Taiyuan Shanxi Province, 030001, China; b Department of Clinical Laboratory, Central Hospital, 12th Bureau Group of China Railway, Taiyuan Shanxi, 030053, China; c Department of Physiology, Key Laboratory of Cellular Physiology Co-constructed by Province and Ministry of Education, Shanxi Medical University, Taiyuan Shanxi, 030001, China; d Department of Biology, Taiyuan Normal University, Taiyuan Shanxi, 030031, China
  • 【年份】2015
  • 【卷号】Vol.8 No.1
  • 【ISSN】1756-3305
  • 【关键词】AMA1 Mucosal vaccine Peptide epitope RON2 RON4 Toxoplasma gondii 
  • 【摘要】 Background: Toxoplasma gondii is a ubiquitous protozoan intracellular parasite, the causative agent of toxoplasmosis, and a worldwide zoonosis. Apical membrane antigen-1 and rhoptry neck protein are involved in the invasion of T. gondii. Methods: T...
  • 【文献类型】 期刊
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