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Protective immunity induced by peptides of AMA1, RON2 and RON4 containing T-and B-cell epitopes via an intranasal route against toxoplasmosis in mice

  • 【作者】Tie-E Zhang,Li-Tian Yin,Run-Hua Li,Hai-Long Wang,Xiao-Li Meng,Guo-Rong Yin
  • 【刊名】Parasites and Vectors
  • 【作者单位】1. Research Institute of Medical Parasitology, Shanxi Medical University, Xinjian South Road, Taiyuan, Shanxi Province, 030001, China 2. Department of Clinical Laboratory, Central Hospital of the 12th Bureau Group of China Railway, Taiyuan, Shanxi, 030053, China 3. Department of physiology, Key Laboratory of Cellular Physiology Co-constructed by Province and Ministry of Education, Shanxi Medical University, Taiyuan, Shanxi, 030001, China 4. Department of Biology, Taiyuan Normal University, Taiyuan, Shanxi, 030031, China
  • 【年份】2015
  • 【卷号】Vol.8 No.1
  • 【页码】15
  • 【ISSN】1756-3305
  • 【关键词】Toxoplasma gondii AMA1 RON2 RON4 Peptide epitope Mucosal vaccine 
  • 【摘要】 Background Toxoplasma gondii is a ubiquitous protozoan intracellular parasite, the causative agent of toxoplasmosis, and a worldwide zoonosis. Apical membrane antigen-1 (AMA1) and rhoptry neck protein (RON2, RON4) are involved in the invasion of T....
  • 【文献类型】 期刊
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