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Fluoride induces apoptosis and alters collagen I expression in rat osteoblasts

  • 【作者】Yan, Xiaoyan,Yan, Xiaoting,Morrison, Alex,Han, Tianlong,Chen, Qinglin,Li, Ji,Wang, Jundong
  • 【刊名】Toxicology Letters
  • 【作者单位】1 Shanxi Key Laboratory of Ecological Animal Science and Environmental Medicine, Shanxi Agricultural University, Taigu, Shanxi 030801, PR China 2 Department of Biology, Taiyuan Normal University, Taiyuan, Shanxi 030012, PR China 3 Department of Pharmacology and Toxicology, School of Medicine and Biomedical Sciences, University at Buffalo-SUNY, Buffalo, NY 14214, USA 4 Graduate School of Shanxi Medical University, Taiyuan, Shanxi 030001, PR China
  • 【年份】2011
  • 【卷号】Vol.200 No.3
  • 【页码】133-138
  • 【ISSN】0378-4274
  • 【关键词】Collagen I collagen I Fluorescence-activated Cell Sorter Fluoride fluoride Osteoblasts osteoblasts phosphate buffered saline propidium iodine sodium fluoride 
  • 【摘要】 In this study we investigated apoptosis and expression of the collagen I gene in newborn rat osteoblasts by the administration of varying concentrations of fluoride . Sodium fluoride at concentrations of 0, 0.5, 5, 10, and 20mg/L was administered t...
  • 【文献类型】 期刊
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