【作者】Yan-Mei Yan，Meng-Liang Wang，Yu-Long Liu，Ying-Chun He
【刊名】Tetrahedron
【作者单位】b Institute of Applied Chemistry, Shanxi University, Taiyuan, 030006, PR China a Department of Chemistry, Taiyuan Normal University, Jinzhong, 030619, PR China c Shanxi Bethune Hospital & Shanxi Academy of Medical Sciences, Taiyuan, 030006, PR China
【年份】2020
【页码】131389
【ISSN】0040-4020
【关键词】γ-lactam Regioselective Metal-free Propenoic acid Ugi reaction
【摘要】 A new one-pot and regioselective synthesis of functionalized γ-lactams by a metal-free Ugi 4CR/intramolecular 5-exo-dig cyclization sequence under mild conditions has been developed. The reaction of propenoic acid, aldehydes, amines, and isocyanides ...
