【刊名】Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences
【作者单位】a Department of Biology, Taiyuan Normal University, 030031 Shanxi, China; b Graduate Institute of Pharmaceutical Chemistry, Luliang University, 033000 Shanxi, China; c Analytical Sciences, Interbio Co. Ltd., 201203 Shanghai, China
【年份】2012
【卷号】Vol.906
【页码】63-68
【ISSN】1570-0232
【关键词】Application Capillary zone electrophoresis Optimization Therapeutic monoclonal antibody Validation
【摘要】 This work aimed to develop a rapid capillary zone electrophoresis method to provide abundant purity and identity information of monoclonal antibodies. The CZE running buffer system was optimized to be 20. mM acetate-acetic acid together with the co...